FPR2 and Alzheimer disease: Of note, several studies either linked a dysfunctional LX-FPR2 axis to the pathogenesis of many conditions or reported a therapeutic effect of LX administration on many different diseases that are critically associated with oxidative stress, including Alzheimer's disease (AD) [42], arthritis [43], asthma [44], diabetes [45], atherosclerosis [46], and inflammatory bowel diseases (IBD) [47].