In contrast, CX3CR1+/+ and CX3CR1−/− mice showed similar kinetics for encephalitis score after intranasal and intraperitoneal inoculation, although CX3CR1−/− mice showed rapid clinical signs of encephalitis compared with CX3CR1+/+ mice (Figure 1C, middle and right graphs). Here, CX3CR1 is linked to encephalitis.