SLC11A2 and neurodegenerative disease: It is proposed that DMT1 mutant rodents exhibit microcytic, hypochromic anemia (Fleming et al., 1998; Canonne-Hergaux et al., 2000), whereas high-level expression of DMT1 contributes to neurodegenerative diseases (Salazar et al., 2008; Tian et al., 2018).