MEG3 and Alzheimer disease: In addition, dysregulated lncRNAs were also found in neurodegenerative diseases in human, such as lncRNA BACE1-AS and BC200 (Alzheimer’s disease, AD), PINK1-AS (Parkinson’s disease), NEAT1 and MEG3 (Huntington’s disease), AS C9ORF72 (amyotrophic lateral sclerosis) and so on (Wan et al., 2017).