Additionally, the Stearoyl-CoA desaturase (SCD) indices (FFA 16:1/16:0, FFA 18:1/18:0) analysis showed increased SCD indices in the symptomatic SCA3 group as compared with the Pre-SCA3 group and control group (P < 0.001; Table 4). The gene discussed is ATXN3; the disease is Machado-Joseph disease.