Finally, a frameshift mutation (p.S552Ffs∗5) in heterozygous state with the benign p.T1236M missense variant has been identified in one late onset PD patient from Moroccan consanguineous parents (Bouhouche et al., 2017), correlating Synj1 lesions to the risk of PD development. This evidence concerns the gene SYNJ1 and Parkinson disease.