EIF2AK3 and Parkinson disease: Similar results were obtained in pink1/parkin PD models, where mitofusin contacts with damaged mitochondria sustain PERK signaling, while suppression of PERK signaling by using GSK2606414 or by genetic inhibition has a neuroprotective effect (Celardo et al., 2016), suggesting common molecular features between PARK20 and other PD types.