Consistent with the literatures, our results show that the DEGs related to immune response are significantly upregulated following Bb infection such as IL6ST, CSF1R, C1QTNF7, CX3CR1, and CCL24 (Additional files 1–3: Supplementary Table S1–S3) and the complement and coagulation cascades which can regulate the immune response and inflammation are still active 24 h after Bb infection comparing control and infected tissue samples (Figure 5C). The gene discussed is IL6ST; the disease is infection.