C9orf72 and amyotrophic lateral sclerosis: To date, no studies have extensively characterized the specific transcriptional profile of vulnerable vs. susceptible MNs in TDP-43, C9orf72 FUS or other models of ALS, similar to those performed in SOD1G93A mice and ALS patients (Hedlund et al., 2010; Brockington et al., 2013).