An inverse correlation between PTX3 levels and BMI, fat BMI, and serum albumin was described by Miyamoto et al. [40] in two independent cohorts of CKD patients; it was also shown that PTX3 is a better predictor of fat BMI than CRP in both ESRD patients on maintenance haemodialysis and in stage 5 CKD patients referred to start dialysis. This evidence concerns the gene CRP and chronic kidney disease.