For this purpose, we analyzed serpinA3/Alpha-1-antichymotrypsin levels in patients diagnosed with class III, IV and V lupus nephritis, focal and segmental glomerulosclerosis (FSGS), ANCA associated vasculitis (AAV), and compared them with healthy volunteers. The gene discussed is SERPINA3; the disease is anti-neutrophil cytoplasmic antibody-associated vasculitis.