Socio demographic variables (Sex, Age, Marital status, Income, Education, Occupation, Religion, and Residence), Medical and morbidity variables (Diarrhea, Current clinical condition, vomiting, Eating problems, Opportunistic infections, Intestinal parasite, Loss of appetite), Nutritional variables (Nutritional counseling, Nutritional support, feeding style change), Clinic, treatment and accessibility variables (CD4 level, Side effect of drugs, WHO clinical staging, Adherence, Drug regimen type, Duration of ART, Distance from a health center) were independent variables. This evidence concerns the gene CD4 and Opportunistic infection.