In regression analysis including the covariates age, diabetes, amount of transfused units of red blood cells, fresh frozen plasma and platelets, caval clamping time and baseline creatinine, urinary [TIMP-2] × [IGFBP-7] measured at T1, T2 and T3 was not associated with any AKI (P = 0.09, P = 0.54 and P = 0.15, respectively) and severe AKI (P = 0.1, P = 0.77 and P = 0.82, respectively). This evidence concerns the gene IGFBP7 and acute kidney injury.