We have recently highlighted the importance of aggrecan and the ADAMTS family in stent-induced vascular injury.34 Moreover, ADAMTS family members have been implicated in murine thoracic aortic aneurysm formation.24,35 To further investigate whether MFAP4 may be linked to ADAMTS enzymes, we tested the expression levels of ADAMTS-1 and -4. The gene discussed is MFAP4; the disease is thoracic aortic aneurysm.