We have recently highlighted the importance of aggrecan and the ADAMTS family in stent-induced vascular injury.34 Moreover, ADAMTS family members have been implicated in murine thoracic aortic aneurysm formation.24,35 To further investigate whether MFAP4 may be linked to ADAMTS enzymes, we tested the expression levels of ADAMTS-1 and -4. This evidence concerns the gene ACAN and thoracic aortic aneurysm.