Furthermore, ask1-MO larvae exhibited significantly reduced TNF-α and IL-10 transcript levels during either EIB202 or Δtrxlp infection (Fig 5D), while the transcript levels of IL-6, cxcl8, and IFN-γ were not affected compared with infected control-MO larvae (S7B to S7D Fig). The gene discussed is CXCL8; the disease is infection.