It is well documented that more than half of human cancers contain inactive p53 mutant proteins (Bieging, Mello, & Attardi, 2014; Brosh & Rotter, 2009; Trepel, Mollapour, Giaccone, & Neckers, 2010) and these mutant p53 in cancers were protected by the 90 kDa heat‐shock protein (Hsp90) (Brosh & Rotter, 2009; Taipale, Jarosz, & Lindquist, 2010). This evidence concerns the gene HSP90AA1 and cancer.