Different types of antibodies are present in different GBS variants [12-13] like anti-GM1 and GD1b in AMAN, anti-GD1a IgG in severe motor axonal GBS, anti-GQ1b IgG in Miller Fisher syndrome, anti- GT1b ganglioside and polysialogangliosides IgG in cranial nerve variants, anti-GD1b IgG in pure ataxic sensory GBS and anti-GM2 IgM in severe GBS with antecedent CMV infection [9]. The gene discussed is CD40LG; the disease is Miller Fisher syndrome.