To confirm that the predicted synergistic interaction between Aurora B and ZAK is cell context-specific, we applied the TIMMA prediction model also to MDA-MB-361, an ER-positive, HER2-positive, and PR-negative breast cancer cell line, as well as to another triple negative cell line, MDA-MB-436 (Supplementary Data 10–11). Here, PGR is linked to breast carcinoma.