VEGF regulates a series of molecular processes that allow tissue to adapt to the conditions that prevail after stroke, such as neurovascular remodeling and repair, neuroprotection, brain plasticity and the recruitment and proliferation of neuronal precursors (Zhang et al., 2000; Ma et al., 2012; Dzietko et al., 2013; Greenberg and Jin, 2013). The gene discussed is VEGFA; the disease is stroke disorder.