Histonedeacetylases (HDACs) control the gene expression and cellularsignalling and histone deacetylases 2 (HDAC2) is over expressed insolid tumors including colon cancer, lung cancer, cervicalcarcinoma, breast cancer, and kidney/cervix cancer and also inAlzheimer's disease 5-7. The gene discussed is HDAC2; the disease is malignant colon neoplasm.