Mip-2 expression was significantly elevated in BAL fluid from infected CF mice at day 3 post-infection, while levels of Mip-2 in infected CF/Hdac6 mice are similar to control groups Hdac6 −/− and WT (CF: 476 pg/mL, CF/Hdac6: 75 pg/mL, (**1p = 0.006), Hdac6 −/−: 39 pg/mL (**2p = 0.002), and WT: 26 pg/mL, (**3p = 0.001)) (Fig. 5A). The gene discussed is HDAC6; the disease is cystic fibrosis.