By day 3, CF mice had significantly more CFU growth (~134,000 CFU/mL) than all other groups (CF/Hdac6: ~80,000 CFU/mL, *2p = 0.04; Hdac6 −/−: ~62,000 CFU/mL, *3p = 0.02; WT: 27,000 CFU/mL, *4p < 0.0001). Here, HDAC6 is linked to cystic fibrosis.