Infected CF mice also had significantly higher levels of IL-1β at day 3 (133 pg/mL) compared to both Hdac6 −/− (48 pg/ml, *4p = 0.03) and WT (29 pg/mL, **5p = 0.006) (Fig. 5B). The gene discussed is IL1B; the disease is cystic fibrosis.