CHRNA9 and cancer: To further validate our strategy and CaMPNet resource, we generated the CHRNA9 CaMPNets to discover PPIs, to illustrate the cellular functions of CHRNA9 in cancers, to determine whether CHRNA9 community-regulated pathways could be utilized to predict prognosis in patients with different cancer types, and to determine whether existing drugs could be repurposed to target CHRNA9 signaling pathway.