SPTCL is distinct from primary cutaneous γ/δ T-lymphomas, which are typically CD4-, CD8-, CD56+, granzyme B+, perforin+, TIA1+, may involve the epidermis and/or dermis [13, 14], may present with panniculitic pattern [15] and invariably have a very poor prognosis [1]. This evidence concerns the gene TIA1 and lymphoma.