GSTM1 and type 2 diabetes mellitus: In this study, we investigated for the first time, the effect of various concentrations of ozone on human Hb in the whole blood of a non-diabetic individual and four diabetic patients (with type II diabetes), in order to place emphasis on a personalized method for the identification of a safe, appropriate and effective concentration(s) of ozone for treatment of diabetic patients in O3-AHT.