Some studies have shown that a fusion of the TTTY15 gene with USP9Y (TTTY15–USP9Y) predicts prostate biopsy results [17,18] in multiple cases of hepatocellular carcinoma, lung cancer, and prostate cancer, suggesting that TTTY15-USP9Y fusion is a potential driver of carcinogenesis. This evidence concerns the gene USP9Y and hepatocellular carcinoma.