LCN2 and kidney disorder: The main feature of the pristane-induced lupus mouse model is its similarity to human LN, characterized by glomerulonephritis with loss of endothelial cells, tubular inflammatory damage and increase of biomarkers of kidney disease such as angiopoietin-2, neutrophil gelatinase-associated lipocalin and kidney-injury molecule-1 [4,5,6,7,8,9,10,11].