IL1B and Kawasaki disease: Previous reports showed that higher CRP was significantly associated with the presence of CAE and AAA.[10, 15] Johnston et al. recently reported that inhibition of interleukin-1β (IL-1β) decreased thoracic aortic aneurysm formation.[24] In addition, in a limited clinical case report presentation, a recombinant IL-1β receptor antagonist, anakinra, decreased the progression of coronary aneurysms in Kawasaki disease.[25] The present results also showed that elevated CRP levels were significantly associated with excessive expansive CA remodelling.