MYCN and neuroblastoma: The majority of reports also showed that neuroblastoma cells with high expression of MYCN were more sensitive to PI3K inhibition and/or that treatment resulted in downregulated N‐Myc protein levels in vitro and in vivo (Cage et al, 2015; Chanthery et al, 2012; Chesler et al, 2006, Erdreich‐Epstein et al, 2016, Johnsen et al, 2008; Vaughan et al, 2016).