For instance, lncRNA SNHG16 plays oncogenic role in glioma via miR‐4518/PRMT5 axis21; lncRNA PVT1 modulates the malignant behaviours of glioma cells via targeting miR‐190a‐5p/miR‐488‐3p22; lncRNA H19 facilitates the glioma progression via regulating miR‐152. This evidence concerns the gene PRMT5 and central nervous system cancer.