CD8A and infection: Consistent with published reports using other viruses, we observed slight systemic immune deficiencies in the response to i.p. infection with MHV-DM in GF mice in both total T cells and virus-specific T cells; only the number of viral-specific CD8+ T cells reached statistical significance (Figure 2—figure supplement 1A–D) (Abt et al., 2012; Ichinohe et al., 2011).