A later study investigated the presence of taxane-metabolizing enzymes in ovarian cancer and found that CYP3A4 is expressed at very low levels in ovarian cancer, while CYP3A5 and CYP2C8 were expressed in the majority of ovarian tumors, regardless of histologic type, stage, or grade [97]. The gene discussed is CYP3A4; the disease is ovarian neoplasm.