Figure 4 shows that Camk2α, CamkV, and Vdac1 mRNA expression was significantly upregulated in the lesion side compared to the no-lesion side in SED-PD and EX-PD (P < 0.01). CamkV and Vdac1 mRNA expression was downregulated in the lesion side of EX-PD compared with the SED-PD (P < 0.01), but Camk2α was slightly upregulated. The gene discussed is VDAC1; the disease is Parkinson disease.