IL1B and periodontal disorder: Cytokines that are known as innate immunity cytokines such as IL-1, IL-6, and TNF-α and IFN-γ, IL-4, IL-10, IL-12, IL-17, IL-18, and IL-37 are some of the known proinflammatory and anti-inflammatory cytokines that have been studied in relation to periodontal diseases [22–32].