FH and breast cancer: In the subgroup that had no personal history of BC/OC but had family history of BC/OC (designated BC/OC(−)FH(+) in Fig. 2a), three models had superb performance: AUC 0.93 (95% CI, 0.81–1.05) for BOADICEA, 0.92 (95% CI, 0.82–1.03) for BRCAPRO, and 0.92 (95% CI, 0.83–1.02) for the Tyrer-Cuzick model.