SDHC and neoplasm: To further investigate the apparent specificity of SDHC epimutations in dSDH wtGIST we explored whether SDHC epimutations might occur in non-wtGIST tumours with (a) DNA hypermethylation or (b) low SDHC expression in order to test the hypothesis that an SDHC epimutation is specific to particular tumour types and/or is not a consequence of generalised tumour DNA hypermethylation.