Three of the most strongly associated genes—MSMB (βDiscovery = −1.63), which encodes the PSP94 tumor suppressor and PrCa biomarker10, NCOA4 (βDiscovery = 0.75), an androgen receptor co-activator, and AGAP7 (βDiscovery = 1.21)—are known targets for the 10q11.22 GWAS variant rs1099399411,12 (Table 1). The gene discussed is AR; the disease is neoplasm.