SLCO4A1 and colorectal carcinoma: Consistent with the findings of TEM, SLCO4A1-AS1 overexpression increased the number of green fluorescent LC3 (Figure 3A, 3C), and down-regulation of SLCO4A1-AS1 expression reduced the number of green fluorescent LC3 (Figure 3B, 3D), which indicated that SLCO4A1-AS1 is an inducer of autophagy in CRC cells.