Loratadine and HE decreased the levels of IL-2, IL-4 (Figure 3B) and IL-17 (Figure 3D) in AR-induced nasal lavage fluid, and the levels were the lowest in Loratadine group, compared with two HE groups (HE25 and HE50) (Figure 3B,C). Here, IL4 is linked to hereditary elliptocytosis.