As shown Table 1, hs-cTnI level was significantly higher in CAD patients with SI than those without (2.6 ± 1.6 vs. 2.1 ± 1.3 ng/l, P < 0.01). Moreover, hs-cTnI level was significantly higher in CAD patients with MACE than those without (3.1 ± 1.6 vs. 2.1 ± 1.2 ng/l, P < 0.01). The cut-off value of hs-cTnI for MACE derived from the Younden J index was 5.2 ng/l. The gene discussed is TNNI3; the disease is coronary artery disorder.