In another study, it has been shown that serum fetuin-B concentrations were significantly higher in patients with T2DM compared to patients with normal glucose tolerance test and prediabetes and positively correlated with plasma glucose in the fasting state and 2 h after meal, fasting insulin, HOMA-IR, first-phase glucose-stimulated insulin and TG (24). The gene discussed is INS; the disease is prediabetes syndrome.