Hsa_circ_0000707, termed circ-CBFB, derived from CBFB on chromosome 16 and aberrantly over-expressed in CLL patients, was determined to promote cell proliferation and suppress apoptosis through miR-607/FZD3/Wnt/β-catenin pathway [77]. Here, CBFB is linked to B-cell chronic lymphocytic leukemia.