LMNA and progeroid syndrome: Blocking of progerin farnesylation by administration of farnesyltransferase inhibitors corrected nuclear structure but failed to alleviate other aging‐associated marks (Glynn & Glover, 2005; Toth et al., 2005), while depletion of progeria via rapamycin‐mediated activation of autophagy improved nuclear morphology and delayed the onset of senescence (Cao et al., 2011).