Cyclin D1 (CCND1), one of the highly conserved members of the cyclin family, was well characterized by a periodicity in protein abundance in cell cycle.24 Dysfunction of CCND1 was closely related with progression of several cancers by causing abnormal proliferation.24 Several reports showed the targeted relationships between CCND1 and miRNAs in cancer. The gene discussed is CCND1; the disease is cancer.