It also hydrolyzes Ang I into Ang-(1–9), which is then converted into Ang-(1–7) by ACE.12 Results from our study showed that oral administration of the rapeseed peptides to SHR for 5 weeks, the mRNA and protein expression of ACE2 were increased compared to the SHR control group, which demonstrates the multi-targeted inhibitory roles of the peptides in modulating RAS components and hypertension in the rats. Here, ACE is linked to Hypertension.