Even in the face of this antiviral effect on the CD4+ T cells ex vivo, we found that both DCs and B cells of HIV-1-infected participants on ART were able to trans-infect autologous CD4+ T cells derived from the same blood samples (Figure 2A and B, respectively) with levels of HIV-1 Gag p24 at least 1 log10 higher than by cis infection (Figure 2C). The gene discussed is CD4; the disease is infection.