As shown by qRT-PCR analysis, CLPP siRNA suppressed expression of MFN1 (HG+siCLPP and HF+siCLPP groups compared with HG+NC and HF+NC groups showed a decrease of 52% and 37%, respectively), and enhanced expression of DRP1 (HG+siCLPP and HF+siCLPP groups compared with HG+NC and HF+NC groups showed an increase of 68% and 35%, respectively) (p < 0.05) (Fig. 3C) (raw data is available as Dataset 5. The gene discussed is CLPP; the disease is hydrops fetalis.