For instance, lincRNA-Cox2 regulates the release of inflammatory mediators and cytokines by stimulation of TLR2 in bacterial infections (Carpenter et al., 2013), and miR-155 exerts an antiproliferative effect on CD8+ T cells in response to the type I interferon signaling (Gracias et al., 2013). Here, TLR2 is linked to bacterial infectious disease.