PVT1 and rheumatoid arthritis: The PVT1 expression in RA-FLSs post transfection was determined by RT-qPCR means, which indicated that the expression of PVT1 was lower in the sh-PVT1 group when compared with the sh-PVT1-NC group (p < 0.05), while higher levels were identified in the oe-PVT1 group in comparison with the oe-PVT1-NC group (p < 0.05) (Fig. 4a).