Given that no significant changes were observed in aripiprazole‐induced apoptosis in MCF‐7 cells pretreated with dibutyryl‐cAMP, an analog of cAMP that stimulates protein kinase A (data not shown), we next examined whether this antiapoptotic function of D2R activation during aripiprazole‐induced apoptosis involved the AMPK pathway in breast cancer cells. Here, PRKAA1 is linked to breast cancer.