IL4 and allergic asthma: In contrast to the cord blood analyses, many of the genes cross-sectionally associated with IgE in whole blood analyses from mid-childhood (ACOT7, ZFPM1, IL4, IL5RA, EPX, and PRG2)8 consistently had lower nasal DNAm among DMRs found for FeNO, total IgE (EPX), environment IgE (ACOT7), and allergic asthma (EPX).