However, another Lxr target gene, Abcg1 [45] was upregulated more than fivefold, whilst transcription of both Srbp1c [31] and Abca1 [46] were comparatively unaffected by infection, suggesting that there may be redundancy in the Lxr pathway involved in regulation of these genes during Plasmodium infection. The gene discussed is ABCA1; the disease is infection.